Food Databanks have been working on the Bioactive Substances in Food Information System bioactives in foods database (eBASIS) since its inception in 2006. eBASIS is a web-based database that contains validated scientific information on the composition of bioactive substances in plant foods.
Improvements in the availability of open access aggregated bioactive composition data is needed within the scientific community for estimation of bioactive consumption in the diet. Due to this, we have begun the process of creating a new bioactives in food composition database, building on the core data within eBASIS to produce a new interface and systems to produce aggregated composition data. This will be connected to our nutrient data, which will allow, for the first time, dietary intake assessment of bioactives to be estimated alongside nutrients.
Definition of Bioactives
Historically, non-nutrient bioactive compounds (or phytochemicals) have not been classified as nutrients, but there is mounting evidence they may help promote optimal human health, especially in relation age-related disease (e.g. cardiovascular disease and cancer). Research suggests that these bioactive compounds found in fruits, vegetables, cereals and nuts, may help slow the ageing process and reduce risk of many diseases including cancer, cardiovascular disease, degenerative eye diseases and osteoporosis. These bioactive compounds can be defined as ‘inherent non-nutrient constituents of food plants with anticipated health promoting/ beneficial and/or toxic effects when ingested’
The eBASIS system (electronic BioActive Substances Information System) is an online database that has been developed to provide access to quality-assessed data describing composition and the biological activity of bioactive compounds in plant foods. eBASIS was developed with previous EU- and EFSA-funding in collaboration with researchers from the University College Cork and the Danish Technical University.
The database contains information extracted from peer-reviewed primary publications and key features include:
- Unique combination of compositional data and biological effects
- Data linked to authoritative plant and plant part lists
- Comprehensive coverage of plant bioactives
- Use of the LanguaL food description system
Within QIB, eBASIS links closely to the Food & Health ISP to underpin research studies as well acquisition of new information about bioactive compound composition including polyphenols, and glucosinolates, and training for the next generation of researchers in the UK and internationally.
eBASIS can be accessed at http://ebasis.eurofir.org by individual user name log in only. If you are interested in trying the database, please email firstname.lastname@example.org. Jenny Plumb has produced a walkthrough on YouTube to demonstrate the contents and functions of eBASIS.
The eBASIS system has its origins in composition databases developed in the 1990s covering quality assessed peer reviewed data on natural toxicants in food plants namely NOTIS (Naturally Occurring Toxicant Information System) developed at the Institute of Food Research (IFR) in Norwich, and TOXIP (Naturally Occurring Toxicants in Food Plants) developed by the Danish Veterinary and Food Administration (DVFA), Copenhagen, Denmark. These two CD version databases were merged using the structure and organisation developed in the EU NETTOX project to produce the first BASIS (Bioactive Substances in Food Information System) database, funded as a Concerted Action under the EU FAIR programme (CT98-4419) from 1999 to 2001. The BASIS database extended the range of compounds covered, and the NETTOX list of food plants most commonly consumed in Europe was included. The aim was to gather data on all these food plants and, for the first time, to include compounds with beneficial health effects, as well as potential toxicants.
The eBASIS database was further developed by QIB, University College Cork (UCC), Danish Technical University (DTU; formerly DVFA) and Danish Food Information into EuroFIR-BASIS with funding from EuroFIR NoE (FP6, 2005-10), and supported by other experts by combining compositional and biological information on potential protective bioactive compounds using information from published papers and similar critical assessment quality systems based on an internet-deployed rather than CD format.
EuroFIR-BASIS was designed to be compatible with the format, structure and organisation of the national nutrient composition databases, as well as common food description systems, such as LanguaL, the international framework for food description, to ensure that similar search terms could be used to search and retrieve information from both nutrients and bioactives from all databases.
The current eBASIS database has composition and bioeffects information on almost 300 major European plant foods supported by data on 24 compound classes covering bioactive compounds, such as glucosinolates, phytosterols, polyphenols and isoflavones, from over 1300 peer reviewed publications.
The ePlantLIBRA database was developed as part of the FP7 PlantLIBRA project.
Food Databanks at QIB, together with EuroFIR AISBL, Danish Technical University, Polytec (Denmark) and University College Cork (Eire) have contributed to the development of ePlantLIBRA, a database describing quality assessed composition, beneficial and adverse effects information of biologically-active compounds in Plant Food Supplements and botanicals ingredients. ePlantLIBRA development was based on three existing databases; eBASIS (Bioactive Substances in Food Information System), developed by EuroFIR; the MoniQA contaminants database, EU FP6-funded MoniQA (Monitoring and Quality Assurance in the total food supply chain) database; and Fera’s HorizonScan database.
ePlantLIBRA was developed to produce a comprehensive, easily searchable database containing quality evaluated scientific information on Plant and Plant Food Supplement (PFS) bioactive compound composition, botanical information, beneficial bioactivity data and case-reports of adverse effects, as well as composition of potential contaminants.
A user-friendly, efficient and flexible interface is provided for searching, extracting, and exporting the data, including the references. Jenny Plumb has produced two walkthroughs to show you the structure and function of the plantlibra database: